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Shao W, Chen R, Lin G, Ran K, Zhang Y, Yang J

doi: 10.36349/easjacc.2020.v02i03.001 17 BanjacA.PerisicT.SatoH.SeilerA.BannaiS.WeissN.et al

ROR = 9.59, 95% CI 9.0910.12), all of which are consistent with established safety profiles documented in the prescribing information

Three distinct subunits have been identified in humans: PFK-M (muscle), PFK-L (liver), and PFK-P (platelet)

Therapeutic response is dose- and time-dependent: The maximal improvements in aminotransferases and liver fat content typically occur around 28 to 30 weeks after initiating therapy, indicating that sustained treatment is necessary to achieve optimal benefit

Srinivasan V, Pandi-Perumal SR, Trahkt I, et al