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Semaglutide and nonarteritic anterior ischaemic optic neuropathy [PMID: 39870391] Laboratory literature summary: Semaglutide and nonarteritic anterior ischaemic optic neuropathy
Olfactory dysfunction, including parosmia, has been associated with liraglutide use 46 , likely reflecting GLP-1R-mediated modulation of odor-evoked insulin secretion and foraging behaviors in the olfactory bulb 51,52
GLP-1 drugs may be prescribed for the following conditions as per American Diabetes Association/European Association for the Study of Diabetes (ADA/EASD) 2025 guidelines 11 : Primary glycaemic indication: GLP-1 RAs are recommended for adults with type 2 diabetes who have not reached their individualised A1C targets (typically when A1C is 1.5% above the agreed glycaemic goal) despite lifestyle measures and foundational therapy such as metformin
Hardan AY, Fung LK, Libove RA, Obukhanych TV, Nair S, Herzenberg LA, Frazier TW, Tirouvanziam R
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