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Levels of iron and ferritin (iron storage protein) in brain tissue are associated with the amount of amyloid deposition (Bulk et al., 2018
In one of these studies, measuring brain GSH levels with in vivo proton MRS yielded a correlation in GSH reduction and decline in cognitive functions with 87.5% sensitivity and 100% specificity ( These redox imbalances also impact astrocytes, which normally synthesize GSH through the consecutive sections of two ATP consuming cytosolic enzymes
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AHK-Cu is not a DHT blocker like finasteride or dutasteride
which have a complete loss of the PLC expression (PLC -/- ) or express the mutant form of PLC (PLC RAm/RAm ) were also used to investigate potential role of PLC in KRAS -driven lung tumor development
