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Murphy and George Minot for discovery of an effective treatment for pernicious anemia using liver concentrate, later found to contain a large amount of vitamin B 12
High-dose therapy may also cause a brief increase in blood pressure, though this usually returns to baseline within a few hours
Whereas vitamin B12 deficiency does develop in many older adults who are getting their recommended daily allowance.) A deficiency in any vitamin can be catastrophic for health
People with certain allergies might be sensitive to B12
This selectivity is important because it suggests the compound affects only its intended target rather than causing widespread metabolic disruption
The mechanism for bronchospasm remains speculative but may involve NO-mediated bronchiolar smooth-muscle relaxation tipping into paradoxical constriction in susceptible individuals
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