These include the GI lining, as well as bones, skin, tendons, ligaments, and muscles [3, 33] Angiogenesis BPC-157 has been shown in animal models to increase angiogenesis through upregulating endothelial growth factor
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Source: Koyuncu et al., 2025 Angiogenesis and Vascular Repair BPC-157 promotes VEGF (vascular endothelial growth factor) expression and the formation of new blood vessels
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Separate mechanistic work confirms exercise itself raises MOTS-c levels in skeletal muscle and blood, linking training load directly to this anti-inflammatory pathway (Gao 2023)