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Although these studies are published in indexed journals, independent replication by other research groups remains insufficient to draw definitive conclusions about therapeutic efficacy in humans

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Indeed, while GSH negatively impact with the expression of late viral proteins (in particular hemagglutinin and matrix), Bcl-2 impairs nuclear-cytoplasmic translocation of viral ribonucleoproteins (vRNPs)

Towards this end, we used HeLa cells in which endogenous PDS5B is silenced by an siRNA targeting the 3-UTR of the PDS5B mRNA and complemented with an ectopically expressed, siRNA resistant form of HA-tagged PDS5B WT or PDS5B 17A

S., Garzon, S., Casarin, J., Franchi, M., & Ghezzi, F