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Berberine, ALA, Omega 3s Berberine is a plant-derived compound with evidence supporting improvements in insulin sensitivity, fat metabolism, and lipid profiles addressing some of the same downstream metabolic issues that AOD-9604 targets

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After four years, the increase in plaque volume was significantly greater in women taking the placebo (+53.1%) than in women taking the garlic supplement (-4.6%), while no significant difference in plaque volume was found between garlic (+1.1%) and placebo (+5.5%) in men (94, 95)