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4.2 Stimuli-responsive nanoplatforms for spatiotemporal drug release The TME of osteosarcoma exhibits distinct physicochemical features, including acidic pH, elevated glutathione levels, and hypoxia, that can be exploited for stimuli-responsive drug release (45, 59)

These include a lack of donor sources, immune rejection reactions, surgical complications, postoperative recovery, and suboptimal outcomes

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Conclusion Ultimately, the best way to treat GERD or reduce symptoms of acid reflux is to make lifestyle adjustments, such as reducing stress and losing weight

Vitamin C is an antioxidant which scavenges free radicals in the body and protects tissues from oxidative stress [10-12,16-20]