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This is especially damaging in neurodegenerative diseases as the chronic inflammatory state directly contributes to neuronal cell death and synaptic dysfunction

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262,263 GLP-1 regulates energy balance and food intake by acting on specific brain regions, especially the hypothalamus, a key area responsible for hunger and fullness sensations

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That binding triggers a release of TNF- and other cytokines that cause local liver injury and spill into the general circulation, according to the research

DNA fiber assay The DNA fiber assay was performed as described previously 51