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Reduced insulin sensitivity, with increases in fasting blood glucose and HbA1c relative to placebo over 12 months in the same controlled trial, a concern for anyone with existing metabolic risk

Does not eat unless advised so by vet Has kidney disease, as calcium balance may already be impaired

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While the biological mechanisms are intriguing, the psychiatric claims remain speculative

Transforming Growth Factor Beta Signaling in Hepatocytes Participates in Steatohepatitis through Regulation of Cell Death and Lipid Metabolism in Mice