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2015;45:E5361
doi: 10.1016/j.cell.2017.04.004 14 O'NeillLAKishtonRJRathmellJ
Thus far there is no known genetic or molecular cause of this disease, however, our research group was the first to publish a possible genetic cause of this disease
First, it means that orforglipron tablets can contain a dose that closely corresponds to the therapeutically active amount, without the massive overage required for peptide formulations
Similarly, the LEADER trial with liraglutide showed a 13% reduction in MACE in patients with type 2 diabetes and high cardiovascular risk
Thomas, M.K., et al
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