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For generation of human organoids, the use of surgically resected human tissue samples was approved by the Ethics Committee of the Medical Faculty of TUM and all participants in this study gave their written informed consent

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In the treatment with two active ingredients the subjects were administered for 16 weeks daily dosing of 5 grams of HC plus 80 mg of vitamin C

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Additionally, experts advise discontinuing dipeptidyl peptidase-4 inhibitors when initiating GLP-1 therapy, as both act on similar pathways