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Furthermore, the thioredoxin-interacting protein facilitates the endoplasmic reticulum (ER) stress-mediated formation of the NLRP3 inflammasome complex and associates oxidative stress with the activation of the NLRP3 inflammasome, instigating mitochondria stress-induced apoptosis and promoting inflammatory cell death, thioredoxin-interacting protein may be a potential therapeutic target for AKI [57, 58]
L-Carnitine: Boosting energy, performance, and heart health L-Carnitine is a naturally occurring molecule that plays an important role in energy metabolism, making it popular with athletes, health enthusiasts, and those looking to improve cardiovascular and cognitive performance
Dysfunctional ETC, in turn, further enhances ROS production and increases the disruption of the mitochondrial respiratory function and mitochondrial integrity [129]
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