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Participants took a daily single dose of 1,000 g of the assigned B12 formulation for 7 days

In WT mice, both Cagrilintide and sCT significantly increased cFos expression in these hindbrain nuclei compared to vehicles, indicating activation of satiety-related pathways

Why it matters: Monitoring helps connect symptom changes with lab response and safe refill planning

This peptide may also contribute to nervous system support and cognitive recovery

UK guidance emphasises the importance of prompt, adequate treatment of confirmed B12 deficiency to prevent irreversible neurological harm

For persistent cases, modern surgical optionssuch as decompression or spinal fusionprovide effective pain relief and restore function