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The SNO synthases convert NO into SNO and then the transnitrosylases transfer NO to the target cysteine generating the S-nitrosylated protein (SNO-protein)

showed that Wnt signaling is active within the otic placode and that Wnt inhibition via - catenin deletion leads to an expansion of the epibranchial domains at the expense of the otic placodal cells

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Glutathione, a naturally occurring antioxidant in the body, is instrumental in protecting cells from damage caused by free radicals