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Patients should contact their healthcare provider if they experience severe or persistent heartburn that does not respond to conservative measures or over-the-counter treatments within 1-2 weeks, as this may indicate more significant gastroesophageal pathology requiring investigation
Rodriguez PJ, Goodwin Cartwright BM, Gratzl S et al (2024) Semaglutide vs tirzepatide for weight loss in adults with overweight or obesity
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In addition, some complexes have significant limitations, such as irradiation dependence in photoactive systems, potential proliferative effects at low concentrations, or toxicity problems associated with lipophilicity or the metal itself
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