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The science isn't quite there if you're looking at things like mood improvement, like if somebody is truly diagnosed with a mental health disorder, such as major depression, says LesLee Funderburk, PhD, RD, CSSD, CSCS, associate professor in nutrition sciences at Baylor Universitys Robbins College of Health and Human Sciences

clinicians should seek specialist endocrinology input, consult trial protocols, and follow GMC prescribing guidance when considering this investigational combination

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All-trans-retinal induces autophagic cell death via oxidative stress and the endoplasmic reticulum stress pathway in human retinal pigment epithelial cells

Angraal S, Khera R, Wang Y, Lu Y, Jean R, Dreyer RP, Geirsson A, Desai NR, Krumholz HM