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The top six groups of psychiatric AEs with the highest number of reports were insomnia ( n = 1,198, 11.70%), anxiety ( n = 1,131, 11.04%), nervousness ( n = 941, 9.19%), depression ( n = 770, 7.52%), stress ( n = 770, 7.52%), and confusional state ( n = 689, 6.73%)

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This happens when your body doesnt get enough energy, which can throw off hormone signals from the brain that control your menstrual cycle