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Recent progress in systemic therapy for advanced hepatocellular carcinoma

If GIN-induced Bdnf expression is caused by the activation of G s - and/or G q -coupled LPA receptors by gintonin, GIN-induced Bdnf expression should be strongly inhibited by NMDAR antagonist or calcineurin inhibitor

Results vary among individuals

OPTIONS Study Phase 2b results announcement (AOD-9604 development terminated)

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