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These mechanisms are closely tied to research on wound healing, recovery support, and anti-inflammatory responses
However, under oxidative stress conditions, Nrf2 dissociates from Keap1 and translocates to the nucleus, where it activates various antioxidant genes, including HO-1, protecting cells from oxidative damage
This creates a double problem during perimenopause when estrogen levels swing from high to low
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Human pathology
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