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Multipathway disease modulation By activating Nrf2 and interconnected pathways, they concurrently suppress pro-inflammatory signaling (e.g., NF-B), reduce apoptotic susceptibility, and improve metabolic efficiency via PGC-1 regulation
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Zhang L, Ding WY, Wang ZH, Tang MX, Wang F, Li Y, et al
In addition to promoting weight loss, activating POMC anorexigenic neurons, and increasing leptin sensitivity, liraglutide reduced gliosis and increased expression of the anti-apoptotic gene Bcl2
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