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Defrre S, Lousse JC, Gonzlez-Ramos R, Colette S, Donnez J, Van Langendonckt A

1 Heart-rate changes can persist longer but tend to plateau or decline as treatment continues

(2007) L-Carnitine treatment reduces severity of physical and mental fatigue and increases cognitive functions in centenarians: a randomized and controlled clinical trial

Whether physiologic dosing of a GHRH analog reaches this threshold is unknown, but the risk cannot be dismissed for high or indefinite use

Finally, N-acetyl-cysteine (NAC) has been shown to partially prevent tolerance development to nitrate-induced antianginal effects

However, these drugs were never originally designed for long-term obesity control