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A medical author takes the view that Mary Todd Lincoln, the wife of American President Abraham Lincoln, had pernicious anemia for decades and died from it in 1882
PMC 4692085
Can You Be B12 Deficient
NNMT expression is significantly upregulated in white adipose tissue during obesity (3-5 fold) and increases with age across multiple tissues, creating a metabolic drain on both the NAD+ pool and the methylation budget
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For example, a study published in the Journal of Alternative and Complementary Medicine found that B12 supplements improved endurance and reduced fatigue in athletes
