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continuously fed a diet containing NAC + Gly to aged male mice for eight weeks, which corrected GSH levels and promoted the expression of GSH synthesis enzymes (GCLC, GCLM and GS) in the heart, liver and kidney, prolonging the lifespan of aged mice [50]

This increased demand can potentially create relative deficiencies in these co-factors, even if their levels were previously adequate

This finding is interpreted as a more aggressive feature, compared with findings of the round or polygonal cell varieties

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