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(linked study) Urva S, et al

Less common but serious: pancreatitis, gallbladder problems, kidney injury (often from dehydration), hypoglycemia (especially with insulin/sulfonylureas), and rare allergic reactions

Because of this, it's generally considered safe for most people

The BMS 2025 Protocol: Optimising Your HRT and Weight Loss Journey The British Menopause Society (BMS) updated its guidance in April 2026 to address the increasing use of GLP-1 receptor agonists among menopausal women