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To test this, GPx1 expression was partially knocked down in macrophages from healthy volunteers and this resulted in increased H 2 O 2 -induced cell death and lipid peroxidation without H 2 O 2 treatment, implying that GPx1 is important in the homeostatic maintenance of cellular lipid redox
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Assay: Glutathione in mouse cells and tissue
Therapeutic interventions targeting this axis, such as resveratrol, and quercetin, show promise by simultaneously modulating gut-joint signaling and suppressing ferroptosis, potentially achieving intestinal barrier recovery and chondrocyte rescue
edulis (Tanguy et al
Mc NY, R de J ZFR, Ag JL et al
