doi: 10.1002/brb3.1505 238 PanagakiTGenglerSHolscherC
Circadian Rhythm: Potential Therapeutic Target for Atherosclerosis and Thrombosis
Common side effects patients should know about: Mild injection-site irritation Transient water retention and joint pain Headaches or shifts in appetite Changes in blood sugar or blood pressure Rare allergic reactions Peptide therapy is generally well-tolerated with minimal side effects when properly dosed
However, overstimulation of melanocytes can cause excess melanin deposition, leading to skin pigmentation or hyperpigmentation
Expert Opin Pharmacother 24(1):105120
The insulin resistance in PCOS might also occur independently of body weight, due to inherited post-receptor defects in insulin signalling that affects metabolism and mitotic pathways, not only in classic insulin target tissues, such as skeletal muscle, liver, and adipose tissue, but also in the non-classical target tissues, such as pituitary and ovary [12, 16]