It is the target for several FDA-approved antidiabetic medications called incretin mimetics: These incretin mimetics are glucagon-like peptide 1 (GLP-1) analogs that mimic the physiological action of GLP-1 and thereby potentiates the incretin effect in type 2 diabetic patients
4,41,42 The 52-week phase 3 open-labeled RCT (PIONEER-2) studied 821 T2D patients needing a second agent after metformin and demonstrated that 14 mg of once-daily oral semaglutide was superior to 25 mg of once-daily empagliflozin, in respect of HbA1c reduction
Kezdj el j letet lni mg ma, s rd t a testedben lv mintkat tbb ezer ves s bevlt termszetes sszetevk segtsgvel
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