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Vegetarian Resource Group

Unfortunately, some patients still show limited response to DMARDs, which puts forward new requirements for special targets and novel therapies

The possible underlying mechanism may involve the improvement of mitochondrial function by modulating the miR-130b-3p/PGC-1 pathway

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Computers in Biology and Medicine

A plethora of PASC clinical symptoms and related metabolic impairments indicate involvement of different pathobiological mechanisms such as (i) virus-induced hypoxia/Warburg effect, (ii) iron (Fe)-redox dysregulation (FeRD), (iii) m- Dys and altered bioenergetics, (iv) oxidative stress (OxS) and cellular damage, (v) immuno-pathogenesis and hyperinflammation, (vi) autoimmunity, (vii) dysbiosis, (viii) re-activation of latent pathogens, (ix) persistent viral reservoirs, and (x) viral-hijacked host cellular factors 22,27,137,138