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If you have prolonged GI losses, monitor potassium and magnesium

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These were reportedly mild to moderate and usually occurred as they increased their dosage

Separate studies demonstrated anti-anxiety effects in rats at remarkably low doses (0.5 mg/kg), with effects appearing within 12 minutes and including increased exploration of open and lighted spaces, a standard measure of reduced anxiety in rodent models

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However, the protective effects of PRLMs depend on the activation of specific receptors, and accumulating evidence highlights the dual nature of receptor signaling