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1 H NMR (400 MHz, DMSO) 8.74 (s, 1H), 8.22 (d, J = 8.3 Hz, 1H), 7.50 7.39 (m, 9H), 7.22 (s, 1H), 7.18 7.09 (m, 6H), 6.91 (t, J = 6.0 Hz, 1H), 4.57 (td, J = 9.0, 4.8 Hz, 1H), 3.50 (d, J = 10.9 Hz, 2H), 3.14 (dd, J = 15.0, 4.9 Hz, 1H), 2.94 (dd, J = 15.0, 9.8 Hz, 1H), 1.34 (s, 9H)

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Evidence from experimental and clinical studies Preclinical data Animal studies have demonstrated that chronic exposure to e-cigarette vapor induces hepatic triglyceride accumulation and lipid droplet formation, hallmark features of MASLD [133]

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Additionally, a potential combination of IF with pharmacological treatments may enhance therapeutic intervention and efficacy by targeting metabolic and inflammatory pathways which normally accounts during physiological brain aging

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