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doi:10.1093/jat/bks078
251,252 In the canonical cascade, ligand binding (e.g., Jagged1/2, DLL1/3/4) to Notch receptors (Notch14) induces a two-step proteolytic cleavage, culminating in the release of the Notch intracellular domain (NICD), a cleaved cytoplasmic signaling domain that mediates intracellular signal transduction, by -secretase
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Cancer Res 44(7):29472951 Overholtzer M et al (2007) A nonapoptotic cell death process, entosis, that occurs by cell-in-cell invasion
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