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Hamilton Depression Rating Scale (HDRS), 23 Beck Depression Inventory (BDI), 24 and Montgomerysberg Depression Rating Scale (MADRS) 25 as standardized mean differences (SMDs) and their corresponding 95% CI at end-of-treatment (negative values favor ALC) using random-effects (REML) models

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A 2024 paper in Science used optogenetics and human fMRI to identify GLP-1 receptor neurons in the dorsomedial hypothalamus as the substrate for the preingestive satiation these drugs produce the sense of fullness before you finish eating