Do not apply serum above 1% daily without cycling
This encourages use of the CPT system as drug target for reduction of gluconeogenesis and restoration of lipid homeostasis, which are beneficial in the treatment of type 2 diabetes mellitus and obesity
Clinically, GLP-1-based therapies offer the additional advantage of established cardiovascular protection and renal benefits, making them particularly attractive for the large proportion of MASLD patients with comorbid cardiovascular disease or type 2 diabetes
Since that trial over a decade ago, interest has only surged
A Combined Approach: GLP-1 Agonists and Bariatric Surgery One exciting area of research and practice is the combination therapy involving both GLP-1 agonists and bariatric surgery, either preoperatively or postoperatively
"Preservation of lean soft tissue during weight loss induced by GLP-1 and GLP-1/GIP receptor agonists: A case series." SAGE Open Medical Case Reports