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[1] [3] For patients with dietary deficiency but without neurological involvement, oral supplementation may be appropriate

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doi: 10.1038/s41392-020-00374-6 3 Abdool KarimS

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It modulates over 4,000 genes involved in tissue remodeling, suppresses pro-inflammatory cytokines (IL-6, TNF-alpha), and activates proteasome and antioxidant pathways (Pickart et al., BioMed Res Int, 2012)

Others use low dead-volume syringes designed to minimize this waste