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For IBS-like discomfort more broadly, the 2021 American College of Gastroenterology clinical guideline on IBS made a conditional recommendation against the use of probiotics for the treatment of global IBS symptoms, citing very low quality of evidence and substantial heterogeneity across strains, doses, and outcomes.[6] The ACG position is the strongest authoritative reading available
2022;10(4):e35606
2010 Jul;13(4):359-65
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