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Kinesin KIF4A is associated with chemotherapeutic drug resistance by regulating intracellular trafficking of lung resistance-related protein
ACS Appl Bio Mater (2024) 7(10):67309
The phenotype of senescent cells is associated with the presentation of specific peptides implicated in the activation of CD8 + lymphocytes
In a phase 2 dose-finding trial, once-weekly Cagrilintide produced clinically meaningful weight loss about 10.8% at the 4.5 mg dose over 26 weeks with gastrointestinal effects the most common adverse events [1]
While more research is needed, this highlights the importance of moderation
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