Beyond their ability to cross the BBB, NPs can be tailored to deliver therapeutic agents precisely to affected brain regions, enabling highly targeted interventions [195]

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Oxidative phosphorylation modulators By competitively inhibiting long-chain 3-keto-CoA sulfatase, trimetazidine shifts myocardial metabolism from fatty acid -oxidation to glucose oxidation, thereby optimizing energy production during episodes of ischemia
doi:10.1007/s12015-025-10911-x
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Prevention and Long-Term Management Prevention of vitamin B12 deficiency anaemia focuses on identifying at-risk populations and implementing appropriate monitoring and supplementation strategies