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The vitamin is a cofactor for methionine synthase, which catalyzes the conversion of homocysteine to methioninerequired for the formation of S-adenosylmethionine, a universal methyl donor for almost 100 substrates, including DNA, RNA, hormones, proteins, and lipids
12,13 GLP-1 RAs are recommended in the treatment guidelines by the American Diabetes Association as well as the American Association of Clinical Endocrinology (AACE) Consensus Statement & European Society of Cardiology for type 2 diabetes mellitus patients with co-morbidities, like established atherosclerotic cardiovascular disease and obesity
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Popular weight loss drugs such as semaglutide (Ozempic, Wegovy, and Rybelsus) and tirzepatide (Mounjaro and Zepbound) may do more than help people lose weight
Diabetes Care 38:1409
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And the cardiometabolic benefits were equally impressive
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