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3,417 adults randomized to cagrilintide 2.4 mg + semaglutide 2.4 mg, cagrilintide alone, semaglutide alone, or placebo for 68 weeks

Lactate accumulation is commonly accepted as a sign of mitochondrial ill-health, indicating that mitochondria are not able to utilize either glucose or lactate as the source of energy [24]

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6 to 20 units per day on a 1 ml insulin syringe, equal to 0.6 to 2 mg per injection

These parameters vary by treatment zone and patient characteristics, but a few consistent standards help guide predictable outcomes

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