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This reduction activates the Cyclophilin A (CypA)-MMP-9 pathway, which is responsible for the breakdown of the BBB, degeneration of pericytes, and loss of CBF [143, 150,151,152]

This makes oxidative stress a big risk factor for ASD

At lower concentrations (0.1-1 M), GHK-Cu demonstrates modest stimulation of melanocyte proliferation and melanin synthesis, suggesting potential utility in vitiligo or other depigmenting conditions

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