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Moreover, besides the enhanced activity of fibroblasts, which are considered essential for collagen synthesis, tissue repair, and regeneration, there was also a potential rise in mast cell activation

The most common method to assess deficiency is by measuring serum or plasma zinc concentration after fasting (354)

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Fourth, because of its multitarget mechanisms of action, dose optimisation must be approached carefully in order to assess therapeutic versus off-target effects

Nanoparticle-based delivery systems have emerged as a promising approach for brain-targeted therapy, provided they exhibit favorable physicochemical and safety profiles (Masserini 2013)

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