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The above cardiac and extracardiac effects outline the cardioprotective mechanisms of SGLT2 inhibitors that stay behind the success of these drugs in the cardiovascular field

GHRP-2: The Potent Dual-Pathway GH Releasing Hexapeptide GHRP-2 growth hormone releasing peptide-2 is a synthetic hexapeptide that stimulates GH secretion through a dual mechanism that makes it distinctly more potent than GHS-R1a agonism alone

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Given that immune cell accumulation plays a vital role in eye diseases pathogenesis, previous researchers have also studied the effect of GLP-1RAs on macrophages and discovered that it could reduce macrophage infiltration in addition to altering macrophage phenotypes in multiple sclerosis and nephropathy (Chiou et al., 2019