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Overview of Clinical Studies Clinical studies on semaglutide have primarily focused on its efficacy in managing type 2 diabetes and obesity
In some cases, a plateau occurred around months 34
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Primary outcomes measured safety through AEs monitoring, anti-drug antibody development, immune cell biomarker changes via flow cytometry, T-cell proliferation assays, and cytokine production in peripheral blood mononuclear cells, while secondary outcomes included clinical response using MS and endoscopic assessment
The average weight loss of patients with a 2.4 mg semaglutide dose reached 9.6% after 12 weeks, 13.8% after six months, and approximately 15% to 20% after a year
