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Description

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FOXO4-DRI represents a transformative breakthrough in senescence research that has fundamentally changed our understanding of cellular aging and opened unprecedented opportunities for studying age-related diseases and interventions

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Substituting these amino acids influenced both the catabolism [49, 52] and neonatal transcytosis [52] of mouse IgG1 fragments in wild-type (WT) mice in a manner that correlated with the binding affinity of the mutated Fc fragments towards mouse FcRn at pH 6.0 [51]

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