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Biology of Reproduction 83 , 690697 Preprint at (2010)

These symptoms often appear when you first start the medication or when your dose increases

I made a stupid mistake in my original reply

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labels in August 2016, following the FDAs May 2016 announcement that the warnings should be added

Deletion of the gene encoding ABCA1, responsible for lipidating ApoE in the CNS, resulted in an increase in A deposition (Wahrle et al., 2005) Conversely, overexpression of ABCA1 resulted in a decrease in A deposition (Wahrle et al., 2008) in amyloid mouse models, suggesting that increasing ApoE lipidation can reduce A pathology