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Contact Us IGF-1 LR3 (Long Arg3-IGF-1) is a synthetic 83-amino-acid analogue of insulin-like growth factor 1, engineered with an N-terminal 13-amino-acid extension and an Arg3 substitution that together confer markedly reduced affinity for IGF-binding proteins (IGFBPs) and extended plasma half-life

The aberrant activation of NRF2 is found in various cancers including the lung, gallbladder, esophagus, breast, head and neck, and renal cancers (Shibata et al

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Rosenfeld WN, Davis JM, Parton L, Richter SE, Price A, Flaster E, et al

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