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Clinical trials evaluating semaglutide have not identified potassium disturbances as a common or characteristic adverse effect of the drug itself

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Specificity was evaluated by comparing the blank biological matrix, i.e., rat plasma and brain tissue homogenates, spiked with the liraglutide and IS to the blank biological matrix

This calcium overload promotes ATP release from astrocytes, activating P2X 7 receptors and intensifying neuroinflammatory responses [421]

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