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based on consistent formation of -helical structure in initial rounds of structure calculations in which no hydrogen bond restraints were defined), inter-molecular PRE restraints (4 non-interacting copies of the spin label to account for different spin label orientations), inter- and intra-molecular NOE restraints, and ambiguous distance restraints for residues showing CSPs upon binding

doi: 10.1007/s10072-009-0013-2

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Combining network pharmacology and transcriptomic strategies to explore the pharmacological mechanism of Total Ginsenoside Ginseng Root and its impact on antidepressant effects

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