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Efficacy is only one part of the decision If the main question is average weight-loss effect, tirzepatide has generally shown greater average weight reduction than semaglutide in obesity-focused clinical research

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The side effects profile of GLP-1 RAs overlaps with IBS symptoms, but with proactive management these side effects are usually temporary and tolerable

human relevance unknown

Caturano A, D'Angelo M, Mormone A, Russo V, Mollica MP, Salvatore T, et al